Description

• Revision of aromatic chemistry and the aldol reaction and a comparison of the condensation chemistry of carbonyl compounds
• Imines-enamines - synthesis of heteroaromatic molecules, including pyrroles, furans, thiophenes, pyridines, quinolines and quinolones, indoles, thiazoles, isoxazoles, pyrazoles and pyrimidines
• Reactivity of heteroaromatic molecules towards electrophiles and nucleophiles and comparison of the basicity of pyrroles, pyridines and other nitrogen-containing heterocycles
• The regiochemistry of substitution reactions and the effect of other functional groups on regiochemistry for a number of heteroaromatic systems including pyrroles, furans, indoles, pyridines and quinolines
• Functionalization and metallation at ring positions and substituents; Synthetic approaches towards more complex heterocyclic systems, including alkaloids, fused heterocycles and heterocyclic chemotherapeutic agents.
   

Compétences visées

The student will be able to: identify the fundamental classes of heterocycles and be aware of methods for the synthesis and derivatization of each;

Contacts

Responsable(s) de l'enseignement

• Philippe Compain

MCC

Les épreuves indiquées respectent et appliquent le règlement de votre formation, disponible dans l'onglet Documents de la description de la formation.

Régime d'évaluation

CT (Contrôle terminal, mêlé de contrôle continu)

Coefficient

3.0