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Inorganic chemistry 2

  • Cours (CM) 24h
  • Cours intégrés (CI) -
  • Travaux dirigés (TD) -
  • Travaux pratiques (TP) -
  • Travail étudiant (TE) -

Langue de l'enseignement : Français

Description du contenu de l'enseignement

Two parts

1) Homogeneous catalysis :
The principal aim of this course will be to elucidate some of the most important concepts of catalyst design and development, focusing on elements that render a particular set of homogeneous catalysts especially effective. Discussions will be framed in the context of some of the more transformative recent advances in olefin metathesis, cross-coupling, nucleophilic additions to carbonyls and imines, allylic substitutions and conjugate additions.

2) Bioinorganic Chemistry:
  • Role of metal ions in biology, essential and non-essential metals
  • Methods and concepts of importance in bioinorganic chemistry
  • Cu-proteins, Cu-enzymes and their models: electron transfer, activation of oxygen and other moelcuels, oxygen transport, etc
  • Zn in bioinorganic chemistry: Zn-enzymes, structural Zn-sites and Zn as messenger
  • Transport, cell-uptake and storage of iron. Regulators of iron in a cell
  • Metals and health: metal related disease and metal-based drugs.

Compétences à acquérir

1) Homogeneous catalysis
This course is designed to impart the ability to evaluate what factors render a particular set of catalysts most effective for a particular problem. Furthermore, I twill teach the student how to use homogeneous catalysis most effectively.

2) Bioinorganic Chemistry
Knowing, applying and recognizing the basic principles of (bio)inorganic chemistry in/to different biological and medicinal relevant systems (metal-biomolecules, bioactive metal-complexes, etc.), including systems not treated in the teaching unit.
Capable of understanding basic bioinorganic chemical experiments and be able to suggest potential experiments to solve a metal-related biological relevant question.

Pré-requis obligatoires

Inorganic Chemistry I and II (S5- S7), Stereochemistry (S5), Organometallic Chemistry (S8), Organic Chemistry Classes (S5 – S7). A basic understanding of transition metal chemistry, thermodynamics and kinetics.
Crystal field theory, Pearson, acid-base, etc. and knowledge of the structure of biomolecules (proteins, lipids, nucleic acids and sugars).

Contact

Faculté de Chimie

1 RUE BLAISE PASCAL
67008 STRASBOURG
0368851672

Responsable

Amir Hoveyda

Peter Faller


MASTER - Chimie